@P.A. Bean: Multiple monitor setups work best, in my opinion, with 4:3 monitors. I don't like widescreen for these kinds of setups. I have a dual monitor setup at home (2x Syncmaster 930bf @1280x1024) and a triple monitor setup at work (same monitors, but triple). I tend to work on the right-one, not the middle one (for the triple setup, you smart-asses). My VS2010 window layout looks like this: http://slash14.nl/cndsa For applications that don't make extensive use of multiple monitors (like word processing, browsers etc.) I usually use a monitor to keep my Email open all the time (Outlook, left screen), some application I regularly switch to but am not working on primarily on the middle screen and the application I'm working with on the right screen.