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cord blood banking
Cord blood can be used for autologous or allogeneic hematopoietic stem cell transplantation (HSCT) Allogeneic and autologous stem cell transplants are different procedures with different clinical indications. Cord blood may serve as a stem cell source of autologous (patient's own haematopoietic stem cells) or allogeneic HSC transplantation (collected from a related donor/sibling/ family member). They are used to treat a particular disease where the underlying disease process does not involve the bone marrow such as neuroblastomas, non-Hodgkin lymphoma, multiple myeloma, aplastic anaemia and certain types of cancer including Ewing sarcoma, Wilms tumour, medulloblastoma, neuroblastoma, breast and testicular cancer. Today, own cord blood stem cells are also being used in clinical trials (studies that explore whether a treatment is safe and effective for humans) for the treatment of cerebral palsy, autism, traumatic brain injury, spinal cord injury, acute burns and more. In an allogeneic transplant, stem cells are collected from a donor and transplanted into the patient. Allogeneic transplants use healthy donor hematopoietic stem cells from an unaffected tissue-matched relative, most often a sibling. Allogeneic transplants are indicated in the treatment of high-risk acute and chronic leukaemia, bone marrow failure syndromes such as severe aplastic anaemia, haemoglobinopathies, relapsed leukaemia and lymphoma.
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cord blood banking is now following The Typepad Team
Feb 23, 2018